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Diabetes is characterized by elevated concentrations of endothelium-derived adhesion molecules, specifically ICAM-1, ICAM-2, VCAM-1, and PECAM-1, which are members of the immunoglobulin-like molecule family located on the surface of endothelial cells
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Thus, it can be that the pleiotropic effect of BPC 157 therapy can be at least partly due to the activation of these receptors and can perceive the direct action of a neurotransmitter
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