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FDA identified no acute toxicity, repeat-dose toxicity, genotoxicity, reproductive toxicity, or carcinogenicity study of either KPV form
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Pregnant women with the MTHFR 677TT genotype had lower serum folate levels (p = 0.042) and higher Hcy levels (p = 0.003), according to a multivariate study by Aline Barnabe et al
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