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PDF) The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI
In ME/CFS elevated plasma tryptophan levels may enhance the conversion of tryptophan to 5-hydroxytryptophan in the brain, potentially leading to central fatigue, a core symptom of ME/CFS (Castell et al., 2015)
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