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An overdose is recognizable by the following signs: Shallow breathing, slow breathing or respiratory failure Small pupils Confusion Unresponsiveness or loss of consciousness Blue skin due to poor circulation In the case of an opioid overdose emergency, call 911 immediately
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Canonically, this involves the decomposition of Sec by selenocysteine β-lyase, producing selenide that is phosphorylated by selenophosphate synthetase 2 (SEPHS2) to generate selenophosphate for Sec-tRNA synthesis [186]
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