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FA metabolism is even considered to be a prerequisite for GSIS since GSIS attenuation was observed in isolated PIs with inhibited triglyceride lipolysis (162, 176), in mice with deleted lipase specifically in β-cells (60) or in ATGL-knockout mice (192)
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The GPX1 Pro200Leu polymorphism (rs1050450) was associated with morbid obesity, independently of the presence of prediabetes or diabetes in women from central Mexico [117]
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