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Abstract COVID-19 induces chromatin remodeling in host immune cells, and it had previously been shown that vitamin B12 downregulates some inflammatory genes via methyl-dependent epigenetic mechanisms
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This, in turn, especially at extremely high concentrations, has been noticed to induce modifications of different molecules, including DNA [159] and proteins [160], which ultimately can be one of the major contributors in the pathogenesis of various neurodegenerative diseases [161]
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