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This inhibition disrupts the ferroptotic signaling cascade, effectively preventing lipid peroxidation and mitigating ferroptosis (106)
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Overexpression of METTL3 markedly promotes the transdifferentiation of CFs into myofibroblasts, both through upregulating the expression of type I/III collagen and mesenchymal fibrosis markers and through activating the TGF-β1-Mad2/3 signaling pathway (10) (Fig
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