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Comparing the effects of metformin and NO on gluconeogenesis-related enzymes, both inhibit PEPCK1, G6Pase, and F1,6BPase and stimulate PK.47,111,120 Unlike metformin, NO inhibits GAPDH110,117 and activates GCK115,116 ( Table 2 )
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doi: 10.1111/j.1471-4159.2012.07649.x
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