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More specifically, to develop the model we used experimental data from two sources: i) isolated adipocytes treated in vitro with the β-adrenergic agonist isoproterenol to stimulate lipolysis, and additionally with insulin to inhibit the isoproterenol-stimulated lipolysis, from [3], and ii) microdialysis measurements of lipolysis in vivo , stimulated with adrenaline/isoproterenol and inhibited by insulin and phentolamine, from [4]
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