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There can be significant discomfort associated with the testing methodology and findings in IC/BPS patients are inconsistent
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Critically, interventions should be layered and time-stamped—aligned to the where, when and how much of each reactive family—to preserve physiological redox cues (e.g., H 2 O 2 -mediated signalling) while preventing convergence onto damaging chemistries (ONOO − formation, Fenton ·OH, runaway lipid peroxidation) (Doll et al
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