b12 injection if not deficient Why Do You Need Injections? · PA Relief Manufacturer Registration Number: 2243072

Vitamin B12 Injections - Brook Street Pharmacy

Methylcobalamin 1500 mcg Uses Common uses of this injection include: This injection improves the low levels of vitamin B12 caused by poor diet, malabsorption, or higher physiological demand

Manufacturer Registration Number: 2243072

Specification:5 mg vial

(2000), Horm Res 53(Suppl 3), PubMed 10971106 Statistics from preclinical literature AOD-9604 = modified fragment of hGH 177–191 + N-terminal Tyr (sequence Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe), molecular weight 1815.1 Da Developed at Metabolic Pharmaceuticals (Australia) based on the work of professor Frank Ng (Monash University) in the 1990s Standard experimental dose in obesity clinical trials: 1 mg/day subcutaneously (Phase 2b, Heffernan et al.) Mechanism: stimulation of β3-adrenergic receptors in adipose tissue, increased lipolysis and fatty acid oxidation without activation of the hGH receptor (no IGF-1 increase) Phase 2b clinical trial (2007, 300 patients): weight reduction ~2.8 kg vs placebo over 12 weeks FDA status: NDI rejection (2014) as a dietary supplement