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For instance, CTAP, a penta-amine derivative, demonstrated 100-fold higher transfection efficiency than conventional DC-Chol/DOPE formulations due to the high charge density of fully protonated polyamines at physiological pH, enabling efficient NA neutralization and condensation [89]
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(1997) Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail
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